TABLE 5.
Gene ontology hit of D -5 and D -6 desaturases
| Human Gene Term | Gene Symbol | D. melanogaster Hit # 1 (Gene Function) | D. melanogaster Hit # 2 (Gene Function) | Human Aligned |
|---|---|---|---|---|
| % | ||||
| Δ-5 Desaturase | FADS1 | CG11162:72.4:3e-13 (FA hydroxylase) | CG1998:71.6:5e-13(FA hydroxylase) | 56 |
| FADS1 | CG6870:64.7:1e-10 (Cyt-b5) | CG2140:55.1:9e-08 (Cyt-b5) | 20 | |
| Δ-6 Desaturase | FADS2 | CG3566:62.4:5e-10 (Cyt-b5) | CG2140:57.4:2e-08 (Cyt-b5) | 16 |
| Stearoyl-CoA desaturase ( D -9-desaturase) | SCD | CG5887 (FA desaturase) | CG5925 (FA desaturase) | 82 |
| Stearoyl-CoA desaturase-5 | SCD5 | CG5887 (FA desaturase) | CG5925 (FA desaturase) | 92 |
| Enlongase | ELOVL6 | CG3971 (very long chain FA elongase) | CG33110 (long-chain FA elongase) | 96 |
Enlongase, ELOVL family member 6, elongation of long-chain FAs (FEN1/Elo2, SUR4/Elo3-like, yeast); FADS, FA desaturases; SCD, stearoyl-CoA desaturase.