Fig. 2.

Monocyte cytokine release promoted by HDL and apoAI, in native state and preincubated with LDLs. The release of MCP1, IL6, IL8, and IL10 expressed as ng/10⁶ cells was evaluated after incubation of monocytes with HDL and apoAI. In preincubation, 0.5 g apoB/L of LDL and 0.5 g apoAI/L of HDL were used. The final amount of HDL and apoAI in each well was 150 μg of apoAI. Cytokine release promoted by HDL is shown in white bars and that by apoAI in striped bars. Data are the mean ± SD of four experiments. Statistical differences with P = 0.068 are indicated with ^# HDL treated versus untreated HDL.