Fig.1.
A highly significant QTL mapped to chr1: 171096284-176523075, Dserum1c. We find this locus is pleiotropic, affecting variation in both cholesterol and free-fatty acids. This QTL contains a number of candidate genes that are well studied in association with CVD risk factors. Additionally, this QTL overlaps previously identified QTL. CVD, cardiovascular disease; QTL, quantitative trait loci.