. 2010 Jan 18;20(10):2333–2347. doi: 10.1093/cercor/bhp310

Table 1.

Electrophysiological properties of 5-HT_3A-expressing neocortical interneurons

Electrophysiological parameters	VIP-cluster (n = 22)	NPY-cluster (n = 31)	Electrophysiological parameters	VIP-cluster (n = 22)	NPY-cluster (n = 31)
(1) Resting potential (mV)	−55.98 ± 3.92	−60.5 ± 5.59	(15) First spike amplitude (mV)	83.82 ± 9.8	75.1 ± 9.72
(1) Resting potential (mV)	VIP-cluster << VIP-cluster		(15) First spike amplitude (mV)	NPY-cluster << VIP-cluster
(2) Input resistance (MΩ)	761.45 ± 306.46	391.92 ± 124.15	(16) Second spike amplitude (mV)	78.80 ± 8.86	70.6 ± 10.6
(2) Input resistance (MΩ)	NPY-cluster <<< VIP-cluster		(16) Second spike amplitude (mV)	NPY-cluster < VIP-cluster
(3) Time constant (ms)	40.61 ± 19.53	25.65 ± 12.09	(17) First spike duration (ms)	0.95 ± 0.37	1.8 ± 0.53
(3) Time constant (ms)	NPY-cluster << VIP-cluster		(17) First spike duration (ms)	VIP-cluster <<< NPY-cluster
(4) Membrane capacitance (pF)	56.94 ± 25.39	66.20 ± 25.52	(18) Second spike duration (ms)	0.99 ± 0.38	2.00 ± 0.52
(4) Membrane capacitance (pF)	VIP-cluster − NPY-cluster		(18) Second spike duration (ms)	VIP-cluster < < < NPY-cluster
(5) Sag index (%)	12.09 ± 7.83	5.84 ± 6.02	(19) Amplitude reduction (%)	5.78 ± 5.1	5.99 ± 6.98
(5) Sag index (%)	NPY-cluster << VIP-cluster		(19) Amplitude reduction (%)	VIP-cluster − NPY-cluster
(6) Rheobase (pA)	17.72 ± 9.22	64.83 ± 71.36	(20) Duration increase (%)	4.54 ± 2.69	11.43 ± 15.53
(6) Rheobase (pA)	VIP-cluster << NPY-cluster		(20) Duration increase (%)	VIP-cluster << NPY-cluster
(7) First spike latency (ms)	133.00 ± 147.21	243.01 ± 235.14	(21) First spike, AHP max (mV)	−16.07 ± 4.1	−12.10 ± 3.89
(7) First spike latency (ms)	VIP-cluster − NPY-cluster		(21) First spike, AHP max (mV)	VIP-cluster << NPY-cluster
(8) Adaptation (Hz/s)	−12.12 ± 21.59	4.1 ± 24.28	(22) Second spike, AHP max (mV)	−17.58 ± 3.47	−14.30 ± 3.25
(8) Adaptation (Hz/s)	VIP-cluster << NPY-cluster		(22) Second spike, AHP max (mV)	VIP-cluster << NPY-cluster
(9) Minimal steady state frequency (Hz)	14.53 ± 11.21	7.42 ± 5.17	(23) First spike, AHP max latency (ms)	5.82 ± 1.40	15.2 ± 6.88
(9) Minimal steady state frequency (Hz)	NPY-cluster << VIP-cluster		(23) First spike, AHP max latency (ms)	VIP-cluster <<< NPY-cluster
(10) Amplitude accommodation (mV)	0.88 ± 2.18	3.11 ± 0.83	(24) Second spike, AHP max latency (ms)	10.11 ± 14.63	16.3 ± 6.79
(10) Amplitude accommodation (mV)	VIP-cluster << NPY-cluster		(24) Second spike, AHP max latency (ms)	NPY-cluster < < < VIP-cluster
(11) Amplitude of early adaptation (Hz)	57.85 ± 34.81	46.73 ± 27.15	(25) First spike ADP (mV)	1.02 ± 1.72	0.1 ± 0.23
(11) Amplitude of early adaptation (Hz)	VIP-cluster − NPY-cluster		(25) First spike ADP (mV)	VIP-cluster < NPY-cluster
(12) Time constant of early adaptation (ms)	23.93 ± 9.21	33.92 ± 40.48	(26) Second spike ADP (mV)	0.80 ± 1.28	0.0 ± 0.10
(12) Time constant of early adaptation (ms)	VIP-cluster − NPY-cluster		(26) Second spike ADP (mV)	VIP-cluster < NPY-cluster
(13) Late adaptation (Hz/s)	−26.99 ± 18.79	−10.08 ± 17.64	(27) First spike ADP latency (ms)	1.89 ± 2.8	0.2 ± 0.85
(13) Late adaptation (Hz/s)	VIP-cluster << NPY-cluster		(27) First spike ADP latency (ms)	NPY-cluster < VIP-cluster
(14) Maximal steady state frequency (Hz)	75.11 ± 21.36	46.76 ± 17.58	(28) Second spike ADP latency (ms)	1.67 ± 2.56	0.1 ± 0.56
(14) Maximal steady state frequency (Hz)	NPY-cluster <<< VIP-cluster		(28) Second spike ADP latency (ms)	NPY-cluster < VIP-cluster