Figure 4.

The DAT knockdown mice have impaired exploratory preference after short habituation. Mice were first allowed to explore freely in two arms for 10 min and then were allowed to explore freely in all three arms. During the 5-min test, wild-type mice but not knockdown mice spent most of their time exploring the newly introduced arm. However, when mice were first allowed to explore two arms for 60 min, both genotypes spent most of their time exploring the newly introduced arm [genotype × habituation time interaction, F(1,34) = 7.0, P = 0.01]. Error bar represents SEM.