DAS ameliorated the cell damage and the ROS production in primary astrocytes of WT (AQP4+/+) and KO (AQP4−/−). (A) DAS ameliorated the cell damage of the astrocytes induced by MPP+ (100μM) and LPS (1μg/ml), the morphological analyse was taken under bright field (250×, top) and the cell viability was taken by MTT assay (bottom). * P < 0.05 vs astrocytes from AQP4−/− mice controls (black column), n = 4. (B) DAS reduced the ROS production induced by MPP+ (100μM) and LPS (1μg/ml), we have done three independence experiments, and each result presents the same trend.