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Effects of sorafenib (0.1–30 µM) on migration of different human bladder carcinoma cell lines (RT4, T24, J82). After a scratch injury, microscopic analysis of the cell-free area was performed at 0 h and after 24 h. The area, invaded by tumour cells, was calculated. Original photographs (cell-free area indicated) and quantitative analysis (means ± SEM) of five experiments are shown. *P < 0.05 versus control (anova /Bonferroni).
