Skip to main content
. 2010 Aug;160(7):1741–1753. doi: 10.1111/j.1476-5381.2010.00820.x

Figure 5.

Figure 5

Effect of repeated l-AP4 treatment against 6-OHDA-induced (A) loss of TH-positive cells in the SNpc in the lesion hemisphere, (B) reduction in TH levels in the lesion striatum and (D) reduction in DDC levels. Data are mean ± SEM (A,B) n = 10 for vehicle; n = 6–7 for l-AP4; (D) n = 10 for vehicle; n = 4,7 and 8 for increasing doses of l-AP4. **P < 0.01 and ***P < 0.001 significantly different from vehicle (one-way anova with a Bonferroni post hoc test). (C) Photomicrographs showing TH staining in the striatum and SNpc of animals treated with the optimum dose of l-AP4 (3 nmol) or vehicle; lesion side on right. Scale bar: 500 µm for striatum; 200 µm for SNpc.