Table 2.
ABR thresholds to 8 kHz tone bursts.
| Group | Initial Threshold | Final Threshold | PTS | P |
|---|---|---|---|---|
| Saline + oil (control) (n = 10) | 57.08 ± 8.64 | 83.33 ± 6.15 | 26.25 ± 9.56 | < 0.001 |
| NAC (n = 10) | 55.0 ± 9.42 | 72.0 ± 10.32 | 17.0 ± 10.05* | < 0.001 |
| Furosemide (n = 10) | 62.0 ± 5.09 | 81.5 ± 7.09 | 19.5 ± 8.64* | < 0.001 |
| Furosemide + NAC (n = 10) | 55.5 ± 6.43 | 76.0 ± 7.37 | 20.5 ± 8.95* | < 0.001 |
| Furosemide + ACE +Mg (n = 6) |
58.33 ± 5.16 | 82.50 ± 6.89 | 24.17 ± 3.76 | < 0.001 |
| ACE + Mg (n = 7) |
53.63 ± 8.09 | 76.81 ± 12.50 | 23.18 ± 12.30 | < 0.001 |
Mean ± SD of ABR thresholds to 8 kHz tone bursts in dB pe SPL and the threshold shifts (PTS) in dB and the number of mice in each group tested. The results of two-tailed t-tests with Bonferroni correction comparing initial and final thresholds are shown (in the column of P). PTS in the groups marked * were significantly different from that in the control group - i.e. provided protection.