Table 1.
Demographics and clinical parameters of first and second cohorts of SpA patients.
| First cohort | Second cohort | |||
|---|---|---|---|---|
| USpA | AS | USpA | AS | |
| Number of patients | 28 | 21 | 18 | 23 |
| Age (yr) | 26.4 ± 7.6 | 28.8 ± 8.7 | 39.6 ± 7.3 | 31.8 ± 6.9 |
| Gender | 16M/12F | 21M/0F | 7M/11F | 19M/4F |
| HLA-B27 | 26/28 | 21/21 | 21/22 | |
| Duration (months) | 48.8 ± 47.3 | 116.6 ± 78.2 | ||
| Patients with spinal pain | 28/28 | 21/21 | 18/18 | 23/23 |
| Patients with swollen joints or heels | 4 | 3 | 4 | 5 |
| Patients with hip involvement | 4/28 | 13/21 | ||
| Back pain score | 4.9 ± 1.9 | 6.4 ± 1.5 | 5.2 ± 2.8 | 6.4 ± 1.6 |
| Morning stiffness (minutes) | 17.5 ± 24.6 | 42.9 ± 37.9 | ||
| BAS-G | 5.4 ± 2.0 | 7.6 ± 1.6 | 5.1 ± 1.4 | 4.9 ± 2.1 |
| BASFI | 1.7 ± 1.4 | 7.6 ± 1.6 | 2.5 ± 1.4 | 3.2 ± 1.9 |
| BASDAI | 4.3 ± 1.5 | 5.8 ± 1.1 | 3.9 ± 1.8 | 5.4 ± 1.4 |
| ESR (mm/lst hr) | 22.3 ± 16.5 | 37.3 ± 23.9 | 39.6 ± 7.3 | 25.5 ± 19.8 |
| CRP (mg/l) | 7.2 ± 11.9 | 3.2 ± 2.4 | 1.7 ± 0.9 | 1.4 ± 1.3 |
| Tragus-to-wall (cm) | 10.5 ± 0.7 | 15.2 ± 7.3 | ||
| Occiput-to-wall (cm) | 1.9 ± 4.8 | |||
| Schober (cm) | 4.3 ± 0.9 | 3.3 ± 1.7 | 3.9 ± 2.7 | |
| Lateral flexion of lumbar spine (cm) | 18.5 ± 3.5 | 9.8 ± 5.4 | 12.0 ± 6.1 | |
| Chest expansion (cm) | 4.4 ± 1.1 | 2.1 ± 5.4 | 4.1 ± 1.7 | |
| X-rays with positive sacroiliitis | 0/28 | 21/21 | 0/18 | 23/23 |
Cells with no values indicate that those parameters have not been measured. Upper limit of normal of CRP was 0.8 mg/dl for first cohort and 0.3 mg/dl for second cohort.
All AS patients fulfilled the 1984 Modified New York criteria for AS (38). All USpA patients fulfilled the ESSG criteria for SpA, but did not have features for other subtypes of SpA and did not fulfill the classification criteria for AS (3, 39). BASDAI, BASFI and BAS-G are referenced in (40-42). Scores were on scales of 0 to 10.