Figure 6.

Temporal effects of tridentate, DvPLLCtPCbLDo, SHAL on cells. Cells in each well were treated with ¹¹¹In 8 (A), 18 (B), or 39 nCi (C) on 3 ng of SHAL and 39 nCi and 30 ng of SHAL (D), 3 ng of SHAL alone (E), or untreated (F). Treated Raji cells showed more than a 5-fold increased cell death over 3 days, whereas Jurkat's and untreated cells did not. There was little difference in the cytocidal effect if treated with SHAL alone or ¹¹¹In-SHAL. Data represent means and standard deviations for triplicate samples and are representative of replicate studies that showed reproducible results.