Temporal effects of dimeric, tridentate, (DvPLLCtPCbPPP)2LLDo, SHAL on cells. Cells in each well were treated with 111In 5 (A), 10 (B), or 18 nCi (C) on 1.4 ng of SHAL and 18 nCi and 30 ng of SHAL (D), 3 ng of SHAL alone (E), or untreated (F). Treated Raji cells showed increased cell death over 3 days, whereas Jurkat's and untreated cells did not. Data represent means and standard deviations for triplicate samples and are representative of replicate studies that showed reproducible results.