Skip to main content
. 2008 Dec;23(6):783–795. doi: 10.1089/cbr.2008.0589

Table 1.

Multidentate and Dimeric, Multidentate SHALsa Compared and Their Molecular Weight (MW) in Daltons

Acronym Identity MW
Multidentate
 LeacPLD Acetylated 5-leuenkephalin PEG lysine deoxycholate 1505
 ItPLD Triiodothyronine PEG lysine deoxycholate 1559
 DvLPBaPL Dabsyl-l-valine lysine PEG N-benzoyl-l-arginyl-4-amino-benzoic acid PEG lysine 1317
CtLPTPL 3-(2-([3-chloro-5-trifluoromethyl)-2-pyridinyl]oxy)-anilino)-3-oxopropanionic acid lysine PEG l-thyronine PEG lysinea 1163
CtLPBaPL 3-(2-([3-chloro-5-trifluoromethyl)-2-pyridinyl]oxy)-anilino)-3-oxopropanionic acid lysine PEG N-benzoyl-l-arginyl-4-amino-benzoic acid PEG lysine 1287
DvPLLCtPCbL Dabsyl-l-valine PEG lysine lysine 3-(2-([3-chloro-5-trifluoromethyl)-2-pyridinyl]oxy)-anilino)-3-oxopropanionic acid PEG 4-[4-(4-chlorobenzyl)piperazino]-3-nitrobenzenecarboxylic acid lysine 1765
Dimeric, multidentate
 (LeacPLD)2LP (Acetylated 5-leuenkephalin PEG lysine deoxycholate)2 lysine PEG 3006
 (ItPDP)2LL (Triiodothyronine PEG deoxycholate PEG)2 lysine lysine 3113
 (DvLPBaP)2LL (Dabsyl-l-valine lysine PEG N-benzoyl-l-arginyl-4-aminobenzoic acid PEG)2 lysine lysine 2626
 (DvLPBaPP)2LL (Dabsyl-l-valine lysine PEG N-benzoyl-l-arginyl-4-aminobenzoic acid PEG PEG)2 lysine lysine 2921
 (DvLPBaPPP)2LL (Dabsyl-l-valine lysine PEG N-benzoyl-l-arginyl-4-aminobenzoic acid PEG PEG PEG)2 lysine lysine 3210
 (DvLPBaPPPP)2LL (Dabsyl-l-valine lysine PEG N-benzoyl-l-arginyl-4-aminobenzoic acid PEG PEG PEG PEG)2 lysine lysine 3501
 (DvLCsPBaPPP)2CsLL (Dabsyl-l-valine lysine cysteic acid PEG N-benzoyl-l-arginyl-4-aminobenzoic acid PEG PEG PEG)2 cysteic acid lysine lysine 3666
(DvPLLCtPCbPPP)2LL (Dabsyl-l-valine PEG lysine lysine 3-(2-([3-chloro-5-trifluoromethyl)-2-pyridinyl]oxy)-anilino)-3-oxopropanionic acid PEG 4-[4-(4-chlorobenzyl)piperazino]-3-nitrobenzenecarboxylic acid PEG PEG PEG)2 lysine lysine 4267
a

SHALs containing the “Ct” ligand are in bold. DOTA on the SHAL contributes an additional 400 (or 244 for biotin) Daltons to the MW.