TABLE 2.
All-Cause Mortality and Specific Clinical Events by Smoking Status at Baseline: Strategies for Management of Antiretroviral Therapy Clinical Trial, 2002–2006
| Never Smokers |
Former Smokers |
Current Smokers |
||||
| Clinical Event | No. | Ratea (95% CI) | No. | Ratea (95% CI) | No. | Ratea (95% CI) |
| All-cause mortality | 25 | 0.5 (0.3, 0.7) | 47 | 1.2 (0.9, 1.5) | 95 | 1.5 (1.2, 1.8) |
| AIDS-related disease | 43 | 0.9 (0.6, 1.1) | 34 | 0.9 (0.6, 1.2) | 86 | 1.4 (1.1, 1.7) |
| Major CVD | 33 | 0.7 (0.4, 0.9) | 39 | 1.0 (0.7, 1.3) | 74 | 1.2 (0.9, 1.5) |
| Expanded CVDb | 53 | 1.1 (0.8, 1.4) | 65 | 1.7 (1.3, 2.1) | 120 | 2.0 (1.7, 2.4) |
| Non-AIDS cancer | 35 | 0.7 (0.5, 0.9) | 29 | 0.8 (0.5, 1.0) | 72 | 1.2 (0.9, 1.5) |
| Major Renal disease | 1 | 0.0 (0.0, 0.1) | 9 | 0.2 (0.1, 0.4) | 8 | 0.1 (0.0, 0.2) |
| Major Hepatic disease | 5 | 0.1 (0.0, 0.2) | 8 | 0.2 (0.1, 0.3) | 12 | 0.2 (0.1, 0.3) |
| Bacterial pneumoniac | 38 | 0.8 (0.5, 1.0) | 51 | 1.3 (1.0, 1.7) | 115 | 1.9 (1.6, 2.3) |
Note. CI = confidence interval; CVD = cardiovascular disease.
a
Per 100 person-years.
b
Major CVD events, as well as congestive heart failure, coronary artery disease requiring drug treatment, or peripheral vascular disease.
c
Initial occurrence.