Relative luciferase activity in UtLM cells and UtSMCs transfected with hERα (A, C), hERβ (B, D), and 3×-Vit-ERE-TATA-Luc plasmids that were treated with DMSO (vehicle control, VC), 10 nM E2, or 0.1, 1.0, 10 µM Fen in the presence or absence of 1.0 µM ICI 182,780. Each value was obtained from three independent experiments performed in triplicate. *p< 0.05, **p<0.01, and ***p< 0.001, compared with VC.