Figure 6. VRP-TRP2 humoral anti-tumor effect is mediated by Fc Receptors.
Kaplan-Meier tumor-free survival curves of (A) 7–9 NAÏVE recipient mice per group, transferred with sera from donor mice vaccinated with the indicated VRP; (B) Eight to 14 FcγR −/− or +/− littermate control mice vaccinated with VRP-TRP2 or VRP-GFP; (C) Twelve C3 −/− or +/+ control mice vaccinated with VRP-TRP2 or VRP-GFP. *** P<0.0001, ** P<0.001, * P<0.01.