TABLE 1.

SEQUENCES OF MIRNA PROBES, LNA-MODIFICATION SITES, AND PREDICTED GENE TARGETS

miRNA	Sequence	Predicted target(s)
Let-7g	5′-ct+Gt+A+C+Aa+A+Ct+Actacctca-3′	RAR-β, EGFR
miR-9	5′- tcatacag+C+T+Agataaccaaaga-3′	RXR-α, MAPK
miR-16-2	5′- cgcc+Aat+Atttac+Gtgctgcta-3′	RAR-β, SH3GL2
miR-20	5′- gatggacgtgatat+T+Cgtgaaat-3′	MAPK, cyclin D1
miR-21	5′- tcaacat+Cag+T+Ctgataagcta-3′	MAPK, TP53INP1, NFIB
miR-30e	5′- tccagtCAAGgatgtttaca-3′	RAR-β, Jun
miR-34a	5′- aacaaccagctaagacactgcc-3′	Cyclin D1, c-Met
miR-126	5′- gcattattac+T+Cacggtacga-3′	VEGF
miR-195p	5′- gccaa+Tattt+Ctgtgctgcta-3′	Cyclin D1, MAPK
miR-200a	5′- acatcgtta+Ccagacagtgtta-3′	MAPK, RAR-β
5S	5′- ttagcttccgagatcagacg-3′	N/A

LNA, locked nucleic acid; N/A, not available.

Note: The plus sign (+) followed by a capital letter indicates LNA-modified nucleic acid. Tm (DNA melting temperature) of these miRNAs was justified to approximately 58°C after LNA-modification. The predicted gene targets of miRNAs were obtained from the miRNA database (http://www.microrna.org/). N/A indicates that no targets are available to date.