Table 1.
Overnight sleep study findings
| parameter | control(1) mean±sd [range] |
OSA−(2) mean±sd [range] |
OSA+(3) mean±sd [range] |
Kruskal-Wallis Anova |
Multiple comparison z’ | ||
|---|---|---|---|---|---|---|---|
| H (2,75) = | p-value | groups | p-value | ||||
| Sleep Efficiency Index (%) | 92.3±4.7 | 92.1±5.8 | 90.7±3.3 | 1.78 | 0.4096 | ||
| Sleep Onset Latency (min) | 18±17.2 | 18.8±22.2 | 22.5±21.9 | 0.29 | 0.8633 | ||
| REM latency (min) | 129.3±59.2 | 127±39.3 | 146.9±55.3 | 1.34 | 0.5126 | ||
| Number of awakenings | 5.5±5.6 | 4.5±4.88 | 3.9±2.8 | 0.59 | 0.7431 | ||
| Total sleep time (hr) | 8.2±0.5 | 8.1±0.6 | 7.8±0.5 | 4.59 | 0.1006 | ||
| Stage 1 (% TST) | 6.7±4.9 | 10.7±8.3 | 8.8±8.6 | 4.84 | 0.0890 | ||
| Stage 2 (% TST) | 45.8±7.3 | 46.1±9 | 46.6±12.3 | 0.19 | 0.9099 | ||
| Stage 3 (% TST) | 4.6±2.0 | 6.3±2 | 7.1±3 | 13.50 | 0.0012 | 1 vs. 2: 2.9 1 vs. 3: 2.9 |
0.01 0.01 |
| Stage 4 (% TST) | 16.8±5.1 | 12.9±7.3 | 15.8±7 | 5.56 | 0.0620 | ||
| NREM (% TST) | 18.5±1.7 | 19±1.33 | 19.6±2 | 1.98 | 0.3715 | ||
| REM (% TST) | 25.6±6.9 | 24±5.3 | 21.7±8.1 | 1.51 | 0.4705 | ||
| Apnea Hypopnea Index | 0.56±0.4 [0 – 1.54] |
6.02±2.87 [3.01 – 12.14] |
6.03±2.04 [3.31 – 8.79] |
54.35 | 0.0000 | 1 vs. 2: 6.5 1 vs. 3: 5 |
0.00 0.00 |
| Apnea Index | 0.5±0.38 [0 – 1.54] |
1.72±1.95 [0 – 9.27] |
1.39±1.28 [0 – 3.97] |
17.47 | 0.0002 | 1 vs. 2: 4 | 0.00001 |
| Obstructive Apnea Index | 0.03±0.06 [0 – 0.24] |
1.21±2.13 [0 – 9.15] |
1.11±1.34 [0 – 3.84] |
30.36 | 0.0000 | 1 vs. 2: 4.2 1 vs. 3: 3.6 |
0.00001 0.00001 |
| Hypopnea Index | 0.06±0.09 [0 – 0.26] |
4.3±2.42 [0.45 – 9.87] |
4.64±2 [2.68 – 8.52] |
58.16 | 0.0000 | 1 vs. 2: 6.4 1 vs. 3: 5.2 |
0.000 0.0000001 |
| Obstructive Apnea Hypopnea Index | 0.08±0.1 [0 – 0.38] |
5.5±2.8 [2.29 – 11.92] |
5.75±2.08 [2.93 – 8.79] |
56.22 |
0.0000 |
1 vs. 2: 6.4 1 vs. 3: 5.1 |
0.000 0.0000001 |
| Nadir SaO2 | 94.3±1.5 | 87±6.7 | 83.4±7 | 45.13 |
0.0000 |
1 vs. 2: 6.6 1 vs. 3: 4.9 |
0.000 0.0000001 |
| Spontaneous Arousal Index (%TST) | 8.2±3.8 | 7.3±4 | 6.3±4.6 | 2.06 | 0.3575 | ||
| Respiratory Arousal Index (%TST) | 0.6±0.9 | 5.6±3.9 | 4.3±3.8 | 27.38 |
0.0000 |
1 vs. 2: 4.9 1 vs. 3: 2.8 |
0.0000001 0.02 |
| Total Arousal Index (%TST) | 9.2±3.6 | 13.4±5.6 | 11.2±5.8 | 8.40 | 0.0150 | 1 vs. 2: 2.9 | 0.01 |
| Sleep Pressure Score | 0.05±0.14 | 0.25±0.26 | 0.24±0.22 | 21.70 | 0.0000 | 1 vs. 2: 4.2 1 vs. 3: 2.9 |
0.0001 0.01 |
Italicized: significant without Bonferonni correction.
Bold: significant with Bonferonni correction.