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. Author manuscript; available in PMC: 2011 Feb 1.
Published in final edited form as: Autism Res. 2010 Feb;3(1):1–7. doi: 10.1002/aur.109

Table 2.

Effect of Genotype Expression Group on ABC-CV Irritability Subscale Scores over Time

MMLE Z SE p
Genotype group 0.74 0.66 1.11 0.51
Time (linear) −6.70 −5.75 1.17 <.001
Time (quadratic) 1.04 2.29 0.45 0.02
Group x time (linear) −4.84 −2.89 1.67 0.004
Group x time (quadratic) 2.01 3.09 0.65 0.002
ABC Hyperactivity 0.25 4.20 0.06 <0.001
Age −0.01 −0.58 0.02 0.57
Final dose 0.17 0.74 0.11 0.46

MMLE (Maximum Marginal Likelihood Estimate) represents the estimated model parameters.