Table 14.

Diabetic Retinopathy Progression from Baseline to 1 Year by Baseline Retinopathy Severity Group

Change from Baseline to 1-Year Visit*	Sham N = 233	Ranibizumab N = 303	Triamcinolone N = 150
Baseline severity: Moderately severe NPDR or better, No. (%)	N = 150	N = 182	N = 80
Improved by 2 or more levels	6 (4%)	46 (25%)	20 (25%)
Worsened by 2 or more levels	11 (7%)	5 (3%)	2 (3%)
P value for comparison with Sham		P = 0.08	P = 0.17
Baseline severity: Severe NPDR or worse, No. (%)	N = 83	N = 121	N = 70
Improved by 2 or more levels†	10 (19%)	18 (28%)	6 (13%)
Worsened by 2 or more levels	7 (8%)	1 (1%)	2 (3%)
P value for comparison with Sham		P = 0.03	P = 0.17

NPDR = non-proliferative diabetic retinopathy

^*N = 685; 113 eyes had missing or ungradeable photos at 1 year

^†Excludes 127 eyes with baseline Level 60 (scars of full or partial PRP present; abnormalities of PDR absent)