Table 5.

Effect of treatment of Shigella diarrhea on some biochemical parameters in rats

Treatment	Dose (mg/kg)	Biochemical parameters
		Serum						Cardiac proteins (mg/g)	Hepatic proteins (mg/g)
		RBC (mm-3)	WBC (mm-3)	Hematocrit	Creatinine (μmol/L)	Triglyceride (mmol/L)	Proteins (mg/ml)
Saline control	0	55940 ± 2865	416 ± 75	29.90 ± 1.79	40.75 ± 9.85	0.68 ± 0.16	28.73 ± 3.54	34.34 ± 8.25	95.46 ± 19.20
Methanol extract	100	93,200 ± 9328*	643 ± 145*	36.80 ± 2.14*	26.81 ± 5.65*	1.50 ± 0.18*	40.47 ± 3.88*	57.7 ± 10.15*	177.18 ± 40.10*
n-hexane fraction	80	58,320 ± 3267	458 ± 59	30.00 ± 1.05	38.61 ± 7.49	1.21 ± 0.15*	31.06 ± 6.58	52.73 ± 14.19*	130.63 ± 28.61*
Ethyl acetate fraction	80	91,830 ± 12,726*	627 ± 94*	36.10 ± 1.79*	24.66 ± 1.58*	1.74 ± 0.35*	39.63 ± 1.04*	68.49 ± 10.76*	176.93 ± 16.05*
n-butanol fraction	80	83,090 ± 11,132*	583 ± 122*	32.10 ± 1.66*	28.96 ± 7.24*	1.29 ± 0.19*	30.78 ± 6.79	56.64 ± 5.59*	156.56 ± 47.68*
Aqueous residue fraction	80	56,430 ± 5228	242 ± 81	31.70 ± 1.88*	32.17 ± 7.15*	1.17 ± 0.39*	34.02 ± 5.64*	50.98 ± 8.98*	131.15 ± 38.37*
Loperamide	2.5	95,870 ± 11,586*	864 ± 87*	38.80 ± 3.04*	18.23 ± 7.24*	1.73 ± 0.19*	42.10 ± 2.77*	69.94 ± 10.86*	178.25 ± 8.22*