TABLE 1.

Functional categories of the 313 genes present in the 350-kb duplication

Functional category	No. of genes in duplication	% of total genesa
Virulence, detoxification, adaptation	15	0.38
Lipid metabolism	17	0.43
Information pathways	20	0.51
Cell wall and cell wall processes	35	0.89
Insertion sequences and phages	17	0.43
PE/PPE proteins	14	0.36
Intermediary metabolism and respiration	89	2.27
Regulatory proteins	21	0.54
Conserved hypothetical proteins	85	2.17
All genes in the duplication	313	7.98

^aRelative to the complete H37Rv genome.