FIG. 5.

NP-specific IgM responses in Cxcl13^−/− mice. Wild-type and Cxcl13^−/− mice were immunized intraperitoneally with 50 μg of ⁵⁰NP-Ficoll. Blood samples were obtained on 0 (preimmune) or 7 (immune) days following the immunization, and ²³NP-specific IgM levels were determined by ELISA. Data points represent individual mice, and horizontal bars represent means of results for each group. Statistical significance of the response to immunization was determined by a two-tailed unpaired Student's t test. n.s., not statistically significant.