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. 2010 Jul 6;78(9):3957–3968. doi: 10.1128/IAI.00374-10

TABLE 2.

Antibody response to ornithine carbamoyltransferase protein in cOTC- or PBS-immunized BALB/c mice

Immunization groupa Log10 antibody titerb
IgG2a/IgG1 ratio
IgG IgG1 IgG2a IgG2b IgG3
cOTC antigen + FA 5.1 ± 0.007, 4.8 ± 0.031 3.9 ± 0.068, 3.6 ± 0.046 4.2 ± 0.009, 3.9 ± 0.02 4.5 ± 0.006, 4.5 ± 0.012 3.3 ± 0.007, 3.6 ± 0.0075 2, 2
PBS control <2 <2 <2 <2 <2
a

FA, Freund's adjuvant.

b

Titers were determined by ELISA at days 15 and 30 after the last dose.