TABLE 3.
Results of C. perfringens challenge of mice immunized with ornithine carbamoyltransferase
| Immunization group | Challenge dose (no. of C. perfringens cells given i.p.) | No. of animals challenged | No. (%) of animals that surviveda | Time to death (h) |
|---|---|---|---|---|
| Recombinant ornithine carbamoyltransferase | 1.2 × 108 | 12 | 7 (58.3 ± 8.33)* | 10-12 |
| 1.2 × 107 | 12 | 12 (100 ± 0.0)* | ||
| Adjuvant control | 1.2 × 108 | 12 | 0 (0 ± 0) | 4-6 |
| 1.2 × 107 | 12 | 0 (0 ± 0) | 4-6 |
a
Each challenge dose was given to 3 groups of 4 animals each. Percentages of animals surviving are means ± standard errors. An asterisk indicates that the result was significantly different from that for the control by Student's t test(P ≤ 0.001).