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. 2010 Jun 28;78(9):3763–3772. doi: 10.1128/IAI.00217-10

FIG. 1.

FIG. 1.

nHgbAI/MPL vaccine reduces lesion severity of experimental chancroid at the macroscopic and microscopic levels. (A) Photographs of pig ear lesions. Pigs were either mock immunized with MPL adjuvant only (2 and 4) or immunized with nHgbAI/MPL (1 and 3) and challenged with either H. ducreyi strain 35000HPhgbAI (1 and 2) or 35000HPhgbAII (3 and 4). Photos were taken 1 week after challenge and immediately prior to biopsy. (B) H&E-stained biopsy sections from pig ears 1 week after infection. Pigs were either mock immunized with MPL adjuvant only (6 and 8) or immunized with nHgbAI/MPL (5 and 7) and challenged with either H. ducreyi strain 35000HPhgbAI (5 and 6) or 35000HPhgbAII (7 and 8) (magnification, ×50).