TABLE 1.
ID50s of C. trachomatis D-EC and D-LC isolates for the female mouse genital tract
| Infective dosea (IFU) | Result for the following C. trachomatis challenge isolate at the indicated day postinfectionb: |
|||
|---|---|---|---|---|
| D-EC |
D-LC |
|||
| 3 | 7 | 3 | 7 | |
| 106 | 5/5 | 5/5 | 5/5 | 5/5 |
| 105 | 5/5 | 5/5 | 5/5 | 5/5 |
| 104 | 8/10 | 8/10 | 15/15 | 15/15 |
| 103 | 8/15 | 10/15 | 8/15 | 11/15 |
| 102 | 0/15 | 1/15 | 0/15 | 1/15 |
| 101 | 0/5 | 0/5 | 0/5 | 0/5 |
a
Groups of medroxyprogesterone acetate-treated mice were infected cervicovaginally with 5 μl of EBs.
b
Results are shown as the number of mice yielding inclusion-positive cultures on the indicated day/total number of mice tested. ID50 calculations were performed by the method of Reed and Muench (23) with data for the day 7 culture results. C. trachomatis D-EC ID50, 6.3 × 102; C. trachomatis D-LC ID50, 4.4 × 102.