FIG. 5.

Pathogenicity phenotypes of inv, yadA, irp1, and yopE mutants. C. elegans L4 larvae were exposed to Y. enterocolitica strains WA314, WA314 Δinv (P = 0.0066), WA314/pYVΔyadA (P = 0.0091), WA314 Δirp1 (P = 0.6437), WA314/pYVΔyopE (P = 0.0799), and E. coli OP50 (P < 0.0001). Survival curves are considered significantly different from the survival curve of WA314 when P values are <0.05. Average data of three independent experiments are shown. At least 67 nematodes were used in each experiment (Table 2).