Skip to main content
. 2010 Sep;74(3):378–416. doi: 10.1128/MMBR.00004-10

FIG. 7.

FIG. 7.

Comparison of the lantibiotic operon in B. longum subsp. longum DJO10A with partial operons in B. longum subsp. infantis ATCC 15697 and B. angulatum DSM 20098. Red arrows indicate IS elements, and white arrows indicate the component genes for lantibiotic production, modification, secretion, and immunity. Amino acid sequence identities with B. longum subsp. longum DJO10A are indicated. The asterisk indicates that the lower overall identity is due to an internal gene deletion, with the common gene regions sharing almost 100% identity. Genes: lanR2, response regulator gene; lanK, histidine kinase gene; lanA, lantibiotic prepeptide gene; lanR1, response regulator gene; lanD, prepeptide modification enzyme gene; lanM, lantibiotic modifying enzyme gene; lanI, lantibiotic immunity protein gene; lanT, lantibiotic transporter/protease fusion protein gene. The gene numbers of the gene analogs in B. angulatum DSM 20098 and B. longum subsp. infantis are indicated.