TABLE 9.
Comparison of CRISPR-cas systems in bifidobacteria
| Species | No. of repeats | Groupa | Repeat sequence | Structureb |
|---|---|---|---|---|
| B. longum subsp. longum DJO10A | 43 | I | CAAGCTTATCAAGAAGGGTGAATGCTAATTCCCAGC | c5-c1-c2-repeats |
| B. dentium Bd1 | 17 | I | CAAGTTTATCAAGAAGGGTAGAAGCTAATTCCCAGT | csn1-c1-c2-repeats |
| 81 | II | GTCGCTCTCCTCACGGAGAGCGTGGATTGAAAT | c3-c5-csd1-c1-repeats | |
| B. dentium ATCC 27678 | 15 | I | CAAGTTTATCAAGAAGGGTAGAAGCTAATTCCCAGT | c5-c1-c2-repeats |
| 19 | II | GTCGCTCTCCTCACGGAGAGCGTGGATTGAAAT | c3-c5-csd1-csd2-c4-c1-c2-repeats | |
| B. adolescentis ATCC 15703 | 86 | II | GGTCGCTCTCCTTACGGAGAGCGTGGATTGAAAT | c3-c5-csd1a-csd1b-csd2-c4-c1-c2-repeats |
| B. adolescentis L2-32B | 113 | II | GGTCGCTCTCCTTACGGAGAGCGTGGATTGAAAT | c3-csd2-c4-c1-c2-repeats 2-repeats 1 |
| B. animalis subsp. lactis AD011 | 20 | III | CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT | c3-c_GSU0053-c1-repeats |
| B. animalis subsp. lactis HN019 | 20 | III | CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT | c3-hyp-c_GSU0053-c2-c1-repeats |
| B. animalis subsp. lactis Bl-04 | 22 | III | CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT | csb3-c3-csb2-csb1-c2-c1-repeats |
| B. animalis subsp. lactis DSM 10140 | 20 | III | CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT | csb3-c3-csb2-csb1-c2-c1-repeats |
| B. animalis subsp. lactis Bb-12 | 20 | III | CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT | csb3-c3-csb2-csb1-hyp-c1-repeats |
| B. angulatum DSM 20098 | 139? | IV | GTGTTCCCCGCACACGCGGGGATGATCCC | c3-cse1-cse2-cse4-c5-cse3-c1-c2-repeats |
| B. catenulatum JCM1194 | 34 | IV | GTGTTCCCCGCATACGCGGGGATGATCCC | c3-truncated-cse4-c5-cse3-c1-c2-repeats |
a
CRISPR groups represent elements with identical repeat sequences.
b
c1 to c5, CRISPR-associated cas1 to cas5 genes; csd1-csd2, CRISPR-associated csd1-csd2 family genes; c_GSU0053, GSU0053 family CRISPR-associated gene; cse1 to cse4, CRISPR-associated cse1 to cse4 family genes; csn1, CRISPR-associated csn1 family gene; hyp, hypothetical protein gene; truncated, incomplete draft sequence.