TABLE 2.
Embryonic stage | No. of pups/embryos with characteristic by: |
Total for genotype or phenotype | |||||
---|---|---|---|---|---|---|---|
Genotype |
Phenotype |
||||||
+/+ | +/− | −/− | NDa | Normal | Abnormal | ||
Newborn | 30 | 65 | 0 | 0 | 95 | 0 | 95 |
E10.5 | 2 | 6 | 0 | 3 | 8 | 3 | 11 |
E9.5 | 2 | 4 | 0 | 2 | 6 | 2 | 8 |
E7.5 | 7 | 13 | 4 | 3 | 21 | 6 | 27 |
E3.5 | 11 | 12 | 6 | 3 | 29 | 3 | 32 |
Cultured blastocysts | 17 | 32 | 6 | 8 | 57 | 6 | 63 |
ND, genotype not determined due to failure of PCR.