TABLE 2.
Effects of luteolin on expression of proinflammatory markers in the hippocampus of adult and aged mice1
| Adult |
Aged |
P-values |
|||||
| Control | Luteolin | Control | Luteolin | Age | Diet | Diet × Age | |
| mRNA, fold of adult control | |||||||
| IL-6 | 1.00 ± 0.12 | 0.96 ± 0.07 | 1.51 ± 0.14 | 1.19 ± 0.10 | 0.003 | 0.126 | 0.241 |
| TNFα | 1.00 ± 0.11 | 1.25 ± 0.20 | 2.56 ± 0.25 | 2.26 ± 0.35 | <0.001 | 0.911 | 0.289 |
| MHCII | 1.00 ± 0.16 | 0.62 ± 0.10 | 2.70 ± 0.60 | 1.51 ± 0.51 | 0.003 | 0.059 | 0.323 |
Data are means ± SEM, = 6–7.