TABLE 2.
Relative risk (RR) of incident gout according to coffee, tea, and decaffeinated-coffee consumption1
| Coffee and tea consumption | No. of cases | Person-years | Age-adjusted RR (95% CI) | Multivariate RR (95% CI)2 |
| Coffee | ||||
| 0 mL/d (0 cups/d) | 143 | 327,035 | 1.0 | 1.0 |
| 1–237 mL/d (1 cup/d) | 241 | 410,171 | 0.98 (0.80, 1.21) | 0.97 (0.78, 1.20) |
| 238–947 mL/d (1–3 cups/d) | 470 | 1,111,684 | 0.78 (0.65, 0.95) | 0.78 (0.64, 0.95) |
| ≥948 mL/d (≥4 cups/d) | 42 | 283,257 | 0.37 (0.26, 0.52) | 0.43 (0.30, 0.61) |
| P value for trend | — | — | <0.0001 | <0.0001 |
| Tea | ||||
| 0 mL/d (0 cups/d) | 126 | 384,687 | 1.0 | 1.0 |
| 1–237 mL/d (1 cup/d) | 552 | 1,153,959 | 1.08 (0.89, 1.32) | 1.05 (0.86, 1.28) |
| 238–947 mL/d (1–3 cups/d) | 196 | 543,579 | 0.99 (0.79, 1.24) | 0.92 (0.74, 1.16) |
| ≥948 mL/d (≥4 cups/d) | 22 | 49,922 | 1.62 (1.03, 2.55) | 1.55 (0.98, 2.47) |
| P value for trend | — | — | 0.92 | 0.66 |
| Decaffeinated coffee3 | ||||
| 0 mL/d (0 cups/d) | 227 | 517,738 | 1.0 | 1.0 |
| 1–237 mL/d (1 cup/d) | 375 | 644,208 | 0.99 (0.84, 1.17) | 1.02 (0.85, 1.22) |
| >237 mL/d (>1 cup/d) | 176 | 428,171 | 0.77 (0.64, 0.94) | 0.77 (0.63, 0.95) |
| P value for trend | — | — | 0.01 | 0.02 |
1
Because of missing data, the number of gout cases did not add up to the total.
2
Adjusted for age, total energy intake, BMI, menopause, use of hormonal replacement, diuretic use, history of hypertension, and intakes of alcohol, sugar-sweetened soft drinks, total meats, seafood, chocolate, dairy foods, total vitamin C, and beverages presented in the table. RRs were computed by using a Cox proportional hazards model.
3
Analyses used 1984 as the baseline year.