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Dose-response curves for MK-2048, RAL, and EVG against resistant viruses. Dose-response curves for MK-2048 (A), RAL (B), and EVG (C) are shown for wild-type, G118R, E138K, and G118R E138K viruses. Data are fitted to sigmoidal dose-response (variable slope) curves, from which EC50 values were calculated. Data are from three experiments, and error bars represent the standard error of the mean (SEM).
