TABLE 1.
MK-2048 concentration during selection of virus strain 4742 resistance mutations in CBMCs
wk | MK-2048 concn (μM) | Mutation(s) acquired |
---|---|---|
1 | 0.001 | None |
19 | 0.05 | G118R |
29 | 0.25 | G118R and E138K |
MK-2048 concentration during selection of virus strain 4742 resistance mutations in CBMCs
wk | MK-2048 concn (μM) | Mutation(s) acquired |
---|---|---|
1 | 0.001 | None |
19 | 0.05 | G118R |
29 | 0.25 | G118R and E138K |