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. 2010 Jun 30;84(18):9359–9368. doi: 10.1128/JVI.00644-10

FIG. 7.

FIG. 7.

Biological analysis of P20 and its mutants. (A) Binding activity of P20 and its mutants to the gp41 6-HB core as measured by direct ELISA. (B) SPR analyses of P20 and its variants binding to the gp41 6-HB (3NC). The same amounts (38 μM) of P20 and its mutants were injected at a flow rate of 5 μl/min. Experimental curves (solid line) are overlaid with the fitted curves (dashed line) obtained with the 1:1 binding-with-drifting baseline model. (C) Assessment of inhibitory activities of P20 and its mutants on gp41 6-HB formation detected by sandwich ELISA.