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. 2010 Jul 7;84(18):9533–9545. doi: 10.1128/JVI.01005-10

TABLE 1.

Classification of differentially expressed proteins in RSV-infected A549 nucleia

Gel no. Protein name Common name Accession no. MM (Da) pI F/C Expectation score
1 Vimentin VME P08670 52,406 4.99 −17.43 2.40E−27
Heat shock 70-kDa protein 5 GRP78 EAW87621* 51,140 4.91 −5.36 2.40E−56
Laminin-binding protein RSSA P08865 14,104 7.03 −5.31 3.00E−19
Keratin 8 K2C8 P05787 53,671 5.52 −5.10 6.10E−73
Vimentin VME P08670 52,406 4.99 −4.95 7.60E−68
Vimentin VME P08670 53,653 5.06 −4.40 1.20E−60
Heat shock 70-kDa protein 5 GRP78 P11021 51,140 4.91 −4.24 1.50E−22
Thioredoxin TRX-1 Q09433 11,746 4.82 7.47 1.20E−05
Thioredoxin TRX-1 Q09433 11,746 4.82 5.13 2.40E−13
Ribosomal protein SA RSSA EAW64587* 19,625 8.37 2.36 9.60E−08
Calmodulin 3 Q9BRL5 Q9BRL5 16,496 4.33 2.19 2.70E−05
2 Actin-like protein 6A ACL6A O96019 47,350 5.48 −9.43 1.90E−15
Stress-70 protein, mitochondrial GRP75 P38646 73,734 5.97 −6.15 2.40E−50
Serum album Q56G89 Q56G89 69,039 5.85 −5.80 1.50E−06
Aldehyde dehydrogenase 1 AL1A1 P00352 54,800 6.30 −4.57 1.90E−63
Keratin 18 variant K1C18 P05783 47,957 5.40 −4.50 1.20E−20
Enoyl coenzyme A hydratase 1 ECH1 Q13011 35,735 8.47 −4.34 3.00E−37
Actin-related protein 3 ARP3 P61158 47,341 5.61 −4.18 9.60E−22
Stress-70 protein, mitochondrial HSPA9 P38646 73,734 5.97 −4.04 7.60E−47
Albumin ALBU P02768 65,993 5.69 −3.73 1.20E−05
Peroxiredoxin 3 Prdx3 P30048 27,705 7.11 6.68 2.40E−22
Glutathione S-transferase GST_N 2PGTA* 23,327 5.43 4.19 4.80E−35
Tubulin, alpha, isoform 10 TUB_A XP_001107503* 46,284 4.96 3.82 4.80E−17
Glutathione S-transferase GST_N 2PGTA* 23,327 5.43 2.72 3.00E−20
Peroxiredoxin 4 Prdx-4 Q13162 30,571 5.86 2.66 3.00E−21
Chloride intracellular channel 1 (nuclear) CLIC1 O00299 26,906 5.09 2.36 1.20E−15
Ferritin heavy subunit Q6NZ44 Q6NZ44 21,228 5.12 2.30 2.10E−03
Annexin A2 ANXA2 P07355 40,503 8.41 2.29 1.50E−15
3 Phosphoglycerate kinase 1 PGK EAW98602* 28,434 9.21 −9.11 6.10E−07
Septin 7 SEPT_7 Q16181 48,628 8.76 −7.40 3.00E−07
Cofilin 2 COF2 Q9Y281 18,725 7.66 −5.91 7.60E−10
Enolase 1 variant ENOA P06733 47,111 7.01 −5.38 9.60E−51
Voltage-dependent anion channel 1 VDAC1 P21796 30,754 8.62 −5.35 1.20E−35
Aldehyde dehydrogenase 1 AL1A1 P00352 54,800 6.30 −4.79 4.80E−26
Cleavage and polyadenylation factor CPSF5 O43809 26,153 9.06 −4.30 6.10E−47
Cofilin 1 actin modulating protein COF1 P23528 18,491 8.22 −3.15 4.80E−33
UDP-glucose dehydrogenase UDPG XP_001142450* 47,572 5.64 −3.18 3.80E−53
Ligand of annexin II S100a1 1A4PA* 11,065 7.30 7.06 3.00E−20
Cofilin 1 COF1 XP_866236* 16,801 8.54 6.50 1.50E−12
hCG2017792 CRA_B EAW8645* 32,661 8.50 6.45 2.40E−02
Peroxiredoxin 1 Prdx-1 Q06830 18,964 6.41 5.32 2.40E−50
Anterior gradient 2 homolog Q53G64 Q53G64 19,951 9.03 2.86 1.20E−36
Peroxiredoxin 1 Prdx-1 Q06830 18,964 6.41 2.59 6.10E−40
Cyclophilin A PPIA 5CYH_A* 17,870 7.82 2.12 7.60E−39
Annexin A2 ANXA2 P07355 38,594 7.57 5.92 1.50E−07
Aldose reductase ALDR P15121 35,645 6.56 2.45 6.10E−17
a

Shown are high-probability identifications from MCE prefractionation DIGE 2-DE. For each protein, the gel used for identification, common name, Swiss Prot accession number, molecular mass (MM), isoelectric point (pI), fold change relative to uninfected cells (F/C), and expectation score are given. The expectation score is the number of matches expected if the matches were completely random. An expectation value of 1Ε−3 means the chance was 1 in 1,000 that the match was random. *, Swiss Prot ID not available; GenBank number provided for identification.