Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Antigenic profile of Env immunogens
| Antibody | Titera of YU2 trimer variant |
||
|---|---|---|---|
| wt | 368 | 423/425/431 | |
| sCD4 | 1 | —b | — |
| CD4bs MAbs | |||
| b12 | 1 | — | 0.99 |
| b6 | 1 | 0.28 | 1.07 |
| F91 | 1 | 0.15 | 1.31 |
| F105 | 1 | — | 0.90 |
| CoRbs MAbs | |||
| 17b | 1 | 1.57 | — |
| 48d | 1 | 2.72 | — |
| E51 | 1 | 1.29 | — |
| 2.1C | 1 | 1.51 | — |
| V3 MAb 447 | 1 | 0.90 | 1.06 |
ELISA binding titer relative to that of wt trimers.
—, no detectable binding.
