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Decitabine alters the HIV mutation spectrum. Proviral GFP was sequenced from GFP− HSA+ cells. Each number within a wedge represents a specific mutation, with the value indicating the prevalence of this mutation in terms of the percentage of total mutations. Number of mutations sequenced: no drug, 36; decitabine (Dec), 82; gemcitabine (Gem), 48; decitabine plus gemcitabine, 63.
