TABLE 2.
Detection of JCV DNA in the large T and regulatory regions (RR) of HIV-positive PML, HIV-positive, and HIV-negative patients’ brains, kidneys, bones, spleens, and lymph nodes
| DNA type | Group | No. positive/total no. of specimens tested (%) |
||||
|---|---|---|---|---|---|---|
| Brain | Kidney | Bone | Spleen | Lymph node | ||
| Large T Ag | HIV positive/PML | 9/24 (38) | 1/11 (9) | 0/15 | 4/10 (40) | 1/4 (25) |
| HIV positive | 5/18 (28) | 0/11 | 2/11 (18) | 1/9 (11) | 3/7 (43) | |
| HIV negative | 5/19 (26) | 0/12 | 1/12 (8) | 2/9 (22) | NAa | |
| RR | HIV positive/PML | 6/19 (32) | 2/5 (40) | 3/4 (75) | 4/10 (40) | 2/2 (100) |
| HIV positive | 2/11 (18) | 0/3 | 3/4 (75) | 7/7 (100) | 4/6 (67) | |
| HIV negative | 3/17 (18) | 0/1 | 0/5 | 3/9 (33) | NA | |
a
NA, not available.