TABLE 5.
Distribution of doripenem log2 dilution differences between Etest and agar dilution methods
| Organism group | No. of isolates |
% agreement |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Total | With log2 dilution differencea: |
||||||||||
| ≤−3 | −2 | −1 | 0 | 1 | 2 | ≥3 | Same | ±1 | ±2 | ||
| Enterobacteriaceae | 98 | 4 | 40 | 49 | 5 | 40.8 | 94.9 | 100.0 | |||
| Nonfermenters | 100 | 3 | 3 | 26 | 50 | 8 | 5 | 5 | 50.0 | 84.0 | 92.0 |
| P. aeruginosa | 80 | 2 | 2 | 26 | 39 | 7 | 3 | 1 | 32.5 | 90.0 | 96.3 |
| A. baumannii | 20 | 1 | 1 | 11 | 1 | 2 | 4 | 55.0 | 60.0 | 75.0 | |
| Enterococcus spp. | 49 | 1 | 5 | 19 | 22 | 1 | 1 | 38.8 | 93.9 | 95.9 | |
| Staphylococcus spp. | 97 | 1 | 25 | 56 | 13 | 2 | 25.8 | 84.5 | 97.9 | ||
| S. aureus | 60 | 14 | 38 | 8 | 23.3 | 86.7 | 100.0 | ||||
| CoNSb | 37 | 1 | 11 | 18 | 5 | 2 | 29.7 | 81.1 | 94.6 | ||
| Streptococcus spp., not S. pneumoniae | 60 | 1 | 37 | 18 | 3 | 1 | 61.7 | 93.3 | 98.3 | ||
| Beta-hemolytic group | 39 | 23 | 13 | 2 | 1 | 59.0 | 92.3 | 97.4 | |||
| Viridans group | 21 | 1 | 14 | 5 | 1 | 66.7 | 95.2 | 100.0 | |||
| Total | 404 | 4 | 3 | 37 | 171 | 153 | 27 | 9 | 42.3 | 89.4 | 96.8 |
a
Negative number, Etest result was lower than agar dilution result. Positive number, Etest result was higher than the agar dilution result.
b
CoNS, coagulase-negative staphylococci.