FIG. 4.

Interference with HIV-1 entry of the sulfated XD3 peptide was analyzed in single-round infection assays with R5-tropic (D117III) and X4-tropic (NL4-3) Env pseudotyped luciferase reporter viruses. The infection rate (measured as luciferase activity 48 h after transduction in the cell lysates) decreases with increasing peptide concentrations compared to the rate for virus only (0 μg peptide). The dashed lines correspond to fitted logarithmic curves. Standard deviations refer to triplicate measurements of one representative experiment.