TABLE 1.
Clinical isolates and patients' characteristics
| Isolate/patient codea | HAV genotypeb | Hepatitis severity | Age (yr) | ALTc (IU/ml) | Prothrombin time (%) | Factor V (%) | Encephalopathy | Outcome |
|---|---|---|---|---|---|---|---|---|
| G1B1 | IA | Benign | 37 | 1,455 | 90 | NAd | None | Recovery |
| G1B2 | IA | Benign | 43 | NA | 90 | NA | None | Recovery |
| G1B3 | IA | Benign | 32 | 924 | 83 | NA | None | Recovery |
| G1B4 | IA | Benign | 19 | 3,006 | 79 | NA | None | Recovery |
| G1B5 | IB | Benign | 28 | NA | 83 | NA | None | Recovery |
| G1B6 | IB | Benign | 17 | NA | 58 | 100 | None | Recovery |
| G1S1 | IB | Severe | 22 | 6,456 | 18 | 42 | None | Recovery |
| G1F1 | IA | Fulminant | 52 | 4,180 | 23 | 55 | Grade 1 | Recovery |
| G1F2 | IB | Fulminant | 30 | 2,100 | 17 | 38 | Grade 4 | Death |
| G2B1 | IIA | Benign | 46 | NA | NA | NA | None | Recovery |
| G3B1 | IIIA | Benign | 12 | 2,815 | 81 | NA | None | Recovery |
| G3F1 | IIIA | Fulminant | 43 | 3,696 | 8 | 26 | Grade 1 | Recovery |
a
Each isolate was identified by a 4-letter code which includes the strain genotype (G1, G2, or G3 for genotype I, II, or III, respectively), the hepatitis A clinical presentation (B, S, or F for benign, severe, or fulminant, respectively), and the number of the strain.
b
HAV genotype was determined by the phylogenetic analysis of the VP1/2A junction.
c
ALT, alanine aminotransferase.
d
NA, not available.