FIG. 5.

Liver enzymes and viremia in plasma after MARV Angola challenge. Control and vaccinated animals were exposed to a target dose of 1,000 PFU of MARV Angola. Blood samples were collected before and after infection for the determination of hepatic enzymes and plasma viremia levels. AST and ALT were measured using a General Chemistry 12 reagent disk for the Piccolo analyzer (Abaxis). Plasma viremia was determined by plaque-forming assay on Vero cells. Control and vaccinated animal values are shown by green and black lines, respectively.