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. 2010 Jul 21;84(19):9995–10003. doi: 10.1128/JVI.00505-10

FIG. 4.

FIG. 4.

Hydrogen bond network involving residue 88. (A) Asn88 bridges the terminal helix with Asp30 from the active site and Thr74 from one of the outer beta strands. The red box indicates the region of the protease molecule highlighted in panels B to D. (B) Asn88 in NFVB-WT (PDB code 3EKX). (C) Asp88 in DRVB-D30N/N88D. (D) Ser88 in DRVN88S-WT. Hydrogen bond interactions are indicated by red dashed lines.