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Features of the polymerase subunits. Linear representations of the three polymerase subunits are annotated to show the structurally characterized domains (large boxes). Residues implicated in host adaptation (67) are shown in black. X-ray crystal structures of interaction regions of PA-PB1 (33, 34) and PB1-PB2 (48) are presented with helix colors as in the linear representations.
