FIGURE 4.

Nrdp1 protein is post-transcriptionally suppressed by mouse mammary tumors. A, lysates of normal or tumor mammary tissue from three each NDL transgenic or NxN bigenic mice were blotted with antibodies to ErbB3, Nrdp1, or GAPDH control. B and C, transcript levels of ErbB3 (B) and Nrdp1 (C) were determined by real time PCR analysis of cDNA from mammary glands of NDL and NxN mice and plotted as the tumor to normal ratio. The data in each panel are representative of two or three independent determinations.