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Structural integrity of domains of α5β1 integrin. Time series of root mean square deviations (RMSD) of Cα atoms of α5β1 integrin domains with respect to the respective starting structure when simulated for 200 ns in water (straight line), urea solution (dashed line), and thiorurea solution (dotted line) are shown. A, propeller domain; B, calf-1 domain; C, EGF3 domain.
