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TLR4 deficiency increases animal survival in steatotic animals following ischemia/reperfusion. TLR4 deficiency significantly increased the 24-hour animal survival of HFD mice following 35 minutes of total hepatic ischemia (*P < 0.05, n = 5–8/group). Abbreviations: HFD, high-fat diet; KO, knockout; TLR4, toll-like receptor 4.
