Skip to main content
. Author manuscript; available in PMC: 2010 Sep 13.
Published in final edited form as: Liver Transpl. 2009 Sep;15(9):1101–1109. doi: 10.1002/lt.21782

Figure 3.

Figure 3

TLR4 deficiency decreases hepatic injury in steatotic animals following ischemia/reperfusion. At 24 hours, there was a significant decrease in hepatic injury in TLR4KO HFD animals as assessed by circulating levels of ALT. Animals were sacrificed, and serum was collected prior to surgery (baseline) or 1 or 24 hours post-reperfusion. Values for each group (IU/L) are expressed as the mean ± the standard error of the mean (*P < 0.05 versus TLR4KO HFD, n = 5–8/group). Abbreviations: ALT, alanine aminotransferase; HFD, high-fat diet; ND, normal diet; TLR4, toll-like receptor 4; TLR4KO, toll-like receptor 4–deficient.